The Manchester United lineup that should start against Granada

Manchester United hope to secure a Europa League semi-final place for the second consecutive season when they take on Granada in their second leg clash at Old Trafford.

The Red Devils hold a 2-0 lead from the first leg thanks to goals from star duo Marcus Rashford and Bruno Fernandes, meaning they are heavy favourites to progress through to the next round.

With Harry Maguire, Luke Shaw and Scott McTominay all suspended, plus Rashford nursing injuries, Ole Gunnar Solskjaer must rotate his team but still ensure he has enough quality to see off their plucky La Liga adversaries.

Here's 90min's predicted United lineup.

Man Utd predicted lineup

1. Goalkeeper and Defenders

David De Gea (GK) - The Spaniard finds himself behind Dean Henderson in the pecking order now, but should still have possession of the gloves when it comes to European football.

Aaron Wan-Bissaka (RB) - A regular starter in a defence weakened by suspensions, Wan-Bissaka will need to play from the off for familiarity if nothing else.

Victor Lindelof (CB) - Despite a lingering back issue, Maguire's absence and Eric Bailly's Covid-19 troubles mean Lindelof is likely to be needed here.

Axel Tuanzebe (CB) - Hasn't featured since the Europa League second leg against Real Sociedad, so making a good impression is key.

Alex Telles (LB) - The Brazilian full-back was likely to start anyway, but Shaw's suspension means it's almost certain. His crossing and passing accuracy could be key to unlocking Granada.

2. Midfielders

Fred (CM) - An okay performance against Spurs was topped off with a very important goal, so Solskjaer should keep the momentum going by starting Fred again.

Nemanja Matic (CM) - No McTominay means it's between the Serbian and Pogba, but with the Frenchman likely to be rested for some big games head, Matic may be deployed as a second anchor.

Bruno Fernandes (CAM) - This would ideally be a great chance for Donny van de Beek to play, but Fernandes is too important to drop with other regular first team players out.

3. Forwards

Juan Mata (RW) - The former Chelsea and Valencia man has been a bit-part player this season, but Mata should get some minutes here.

Mason Greenwood (ST) - Three goals and an assist in his last four games, Greenwood is staking his claim for a regular starting spot in the Manchester United attack.

Daniel James (LW) - James missed the weekend game at Spurs with a knock but his availability here could give Rashford a breather.